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Cancer diagnosis in people with severe mental illness: Practical and ethical issues

Howard, Louise M., Barley, Elizabeth A., Davies, Elizabeth, Rigg, Anne, Lempp, Heidi, Rose, Diana, Taylor, David and Thornicroft, Graham (2010) Cancer diagnosis in people with severe mental illness: Practical and ethical issues LANCET ONCOLOGY, 11 (8). pp. 797-804.

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There has been increasing recognition of the high physical morbidity in patients with severe mental illness, but little has been written about cancer in these patients. Therefore, we review the published work on risk of cancer in patients with severe mental illness, treatment challenges, and ethical issues. Severe mental illness is associated with behaviours that predispose an individual to an increased risk of some cancers, including lung and breast cancer, although lower rates of other cancers are reported in this population. Severe mental illness is also associated with disparities in screening for cancer and with higher case-fatality rates. This higher rate is partly due to the specific challenges of treating these patients, including medical comorbidity, drug interactions, lack of capacity, and difficulties in coping with the treatment regimen as a result of psychiatric symptoms. To ensure that patients with severe mental illness receive effective treatment, inequalities in care need to be addressed by all health-care professionals involved, including those from mental health services and the surgical and oncology teams. © 2010 Elsevier Ltd.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Health Sciences
Authors :
Howard, Louise M.
Barley, Elizabeth
Davies, Elizabeth
Rigg, Anne
Lempp, Heidi
Rose, Diana
Taylor, David
Thornicroft, Graham
Date : 6 July 2010
DOI : 10.1016/S1470-2045(10)70085-1
Copyright Disclaimer : Copyright © 2010 Elsevier Ltd. All rights reserved.
Uncontrolled Keywords : antibiotic agent, carbamazepine, clomipramine, clozapine, cyclophosphamide, cytotoxic agent, docetaxel, duloxetine, estrogen, fluoxetine, haloperidol, lapatinib, metoclopramide, neuroleptic agent, paclitaxel, paroxetine, phenothiazine derivative, progesterone, prostate specific antigen, psychotropic agent, recombinant growth factor, risperidone, sertraline, tamoxifen, agranulocytosis, antigen detection, blood dyscrasia, breast cancer, cancer diagnosis, cancer incidence, cancer risk, cancer screening, colonoscopy, colorectal cancer, comorbidity, digital rectal examination, disease severity, drug antagonism, drug contraindication, drug efficacy, drug metabolism, drug potentiation, drug safety, health care access, health care personnel, heart ventricle tachycardia, human, hyperprolactinemia, lifestyle, lung cancer, mammography, manic depressive psychosis, melanoma, mental disease, mental health service, mood disorder, motor dysfunction, neutropenia, pharmacodynamics, pneumonia, postoperative complication, priority journal, prostate cancer, psychosis, QT prolongation, review, risk factor, schizophrenia, sigmoidoscopy, Antineoplastic Agents, Bipolar Disorder, Comorbidity, Drug Interactions, Health Services Accessibility, Health Status Disparities, Humans, Mass Screening, Mental Competency, Mental Disorders, Neoplasms, Psychotic Disorders, Psychotropic Drugs, Schizophrenia
Depositing User : Diane Maxfield
Date Deposited : 19 Jul 2019 16:14
Last Modified : 19 Jul 2019 16:14

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