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Up-Beat UK: A programme of research into the relationship between coronary heart disease and depression in primary care patients

Tylee, Andre, Ashworth, Mark, Barley, Elizabeth, Brown, June, Chambers, John, Farmer, Anne, Fortune, Zoe, Haddad, Mark, Lawton, Rebecca, Mann, Anthony , Mehay, Anita, McCrone, Paul, Murray, Joanna, Leese, Morven, Pariante, Carmine M., Rose, Diana, Rowlands, Gill, Smith, Alison and Walters, Paul (2011) Up-Beat UK: A programme of research into the relationship between coronary heart disease and depression in primary care patients BMC FAMILY PRACTICE, 12, 58.

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Abstract

Background: Coronary heart disease and depression are both common health problems and by 2020 will be the two leading causes of disability worldwide. Depression has been found to be more common in patients with coronary heart disease but the nature of this relationship is uncertain. In the United Kingdom general practitioners are now being remunerated for case-finding for depression in patients with coronary heart disease, however it is unclear how general practitioners should manage these patients. We aim to explore the relationship between coronary heart disease and depression in a primary care population and to develop an intervention for patients with coronary heart disease and depression. Methods/design. This programme of research will consist of 4 inter-related studies. A 4 year prospective cohort study of primary care patients with coronary heart disease will be conducted to explore the relationship between coronary heart disease and depression. Within this, a nested case-control biological study will investigate genetic and blood-biomarkers as predictors of depression in this sample. Two qualitative studies, one of patients' perspectives of treatments for coronary heart disease and co-morbid depression and one of primary care professionals' views on the management of patients with coronary heart disease and depression will inform the development of an intervention for this patient group. A feasibility study for a randomised controlled trial will then be conducted. Discussion. This study will provide information on the relationship between coronary heart disease and depression that will allow health services to determine the efficiency of case-finding for depression in this patient group. The results of the cohort study will also provide information on risk factors for depression. The study will provide evidence on the efficacy and feasibility of a joint patient and professional led intervention and data necessary to plan a definitive randomised controlled trial of the intervention. © 2011 Tylee et al; licensee BioMed Central Ltd.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Health Sciences
Authors :
NameEmailORCID
Tylee, Andre
Ashworth, Mark
Barley, Elizabethe.barley@surrey.ac.uk
Brown, June
Chambers, John
Farmer, Anne
Fortune, Zoe
Haddad, Mark
Lawton, Rebecca
Mann, Anthony
Mehay, Anita
McCrone, Paul
Murray, Joanna
Leese, Morven
Pariante, Carmine M.
Rose, Diana
Rowlands, Gill
Smith, AlisonAlison.Smith@surrey.ac.uk
Walters, Paul
Date : 23 May 2011
DOI : 10.1186/1471-2296-12-38
Copyright Disclaimer : © 2012 Tylee et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Uncontrolled Keywords : article, case management, cohort analysis, coronary artery disease, depression, feasibility study, general practitioner, human, methodology, patient, perception, primary health care, psychological aspect, qualitative research, United Kingdom, Case Management, Cohort Studies, Coronary Disease, Depression, Feasibility Studies, Great Britain, Humans, Patients, Perception, Physicians, Primary Care, Primary Health Care, Qualitative Research, Research Design
Depositing User : Diane Maxfield
Date Deposited : 19 Jul 2019 16:09
Last Modified : 19 Jul 2019 16:09
URI: http://epubs.surrey.ac.uk/id/eprint/850937

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