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The promise of next generation colloids

Creagh-Brown, Ben C and Evans, T.W. (2008) The promise of next generation colloids Critical Care, 12 (3), 147. pp. 1-2.

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The aim of perioperative haemodilution is to reduce loss of red blood cells during elective surgery. The oncotic and molecular characteristics of the various plasma substitutes employed determine how effectively normovolaemia is maintained, and their non-oncotic effects include alterations in microvascular perfusion. In the previous issue of Critical Care, Martini and colleagues assessed the effects of haemodilution with either polyethylene glycol (PEG)ylated albumin or a commercially available hydroxyethyl starch-based colloid in a hamster haemorrhage model. PEGylated albumin was superior to hydroxyethyl starch, as reflected by survival, haemodynamic parameters and assessment of the microcirculation using intravital microscopy. © 2008 BioMed Central Ltd.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
Creagh-Brown, Ben
Evans, T.W.
Date : 14 May 2008
DOI : 10.1186/cc6892
Copyright Disclaimer : © 2008 BioMed Central Ltd
Additional Information : Open Access journal, according to Sherpa Romeo. No further action.
Depositing User : Clive Harris
Date Deposited : 26 Mar 2019 13:01
Last Modified : 26 Mar 2019 13:15

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