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Towards an ultra-rapid smartphone- connected test for infectious diseases

Turbé, Valérian, Gray, Eleanor R, Lawson, Victoria E, Nastouli, Eleni, Brookes, Jennifer C, Weiss, Robin A, Pillay, Deenan, Emery, Vincent, Verrips, C. Theo, Yatsuda, Hiromi , Athey, Dale and McKendry, Rachel A (2017) Towards an ultra-rapid smartphone- connected test for infectious diseases Scientific Reports, 7, 11971.

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Abstract

The development is reported of an ultra-rapid, point-of-care diagnostic device which harnesses surface acoustic wave (SAW) biochips, to detect HIV in a finger prick of blood within 10 seconds (sample-in-result-out). The disposable quartz biochip, based on microelectronic components found in every consumer smartphone, is extremely fast because no complex labelling, amplification or wash steps are needed. A pocket-sized control box reads out the SAW signal and displays results electronically. High analytical sensitivity and specificity are found with model and real patient blood samples. The findings presented here open up the potential of consumer electronics to cut lengthy test waiting times, giving patients on the spot access to potentially life-saving treatment and supporting more timely public health interventions to prevent disease transmission.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
NameEmailORCID
Turbé, Valérian
Gray, Eleanor R
Lawson, Victoria E
Nastouli, Eleni
Brookes, Jennifer C
Weiss, Robin A
Pillay, Deenan
Emery, Vincentv.emery@surrey.ac.uk
Verrips, C. Theo
Yatsuda, Hiromi
Athey, Dale
McKendry, Rachel A
Date : 20 September 2017
DOI : 10.1038/s41598-017-11887-6
Copyright Disclaimer : Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Depositing User : Melanie Hughes
Date Deposited : 28 Aug 2018 15:11
Last Modified : 29 Aug 2018 08:50
URI: http://epubs.surrey.ac.uk/id/eprint/849137

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