University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Nonenhanced ECG-gated quiescent-interval single-shot MRA (QISS-MRA) of the lower extremities: Comparison with contrast-enhanced MRA

Klasen, J., Blondin, D., Schmitt, P., Bi, X., Sansone, R., Wittsack, H.-J., Kröpil, P., Quentin, M., Kuhlemann, J., Miese, F. , Heiss, C., Kelm, M., Antoch, G. and Lanzman, R.S. (2012) Nonenhanced ECG-gated quiescent-interval single-shot MRA (QISS-MRA) of the lower extremities: Comparison with contrast-enhanced MRA Clinical Radiology, 67 (5). pp. 441-446.

Full text not available from this repository.

Abstract

Aim To evaluate electrocardiogram (ECG)-gated quiescent-interval single-shot magnetic resonance angiography (QISS-MRA) for nonenhanced assessment of peripheral artery occlusive disease (PAOD) using contrast-enhanced MRA (CE-MRA) as the reference standard. Materials and methods Twenty-seven patients (mean age 66.6 ± 10.8 years) with PAOD were included in the study. QISS-MRA and CE-MRA of the lower extremity were performed using a 1.5 T MR scanner. In each patient, subjective image quality and the degree of stenosis were evaluated on a four-point scale for 15 predefined arterial segments. Results Twenty-five of the 27 patients were considered for analysis. Subjective image quality of QISS-MRA was significantly lower for the distal aorta, pelvic arteries, and femoral arteries as compared to CE-MRA (p < 0.01), while no significant difference was found for other vascular segments. The degree of stenosis was overestimated with QISS-MRA in 23 of 365 (6.3%) segments and underestimated in two of 365 (0.5%) segments. As compared to CE-MRA, QISS-MRA had a high sensitivity (98.6%), specificity (96%) as well as positive and negative predictive value (88.7 and 99.6%, respectively) for the detection of significant stenosis (≥50%). Conclusion ECG-gated QISS-MRA is a promising imaging technique for reliable assessment of PAOD without the use of contrast material.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine > Department of Clinical and Experimental Medicine
Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Faculty of Health and Medical Sciences
Authors :
NameEmailORCID
Klasen, J.
Blondin, D.
Schmitt, P.
Bi, X.
Sansone, R.
Wittsack, H.-J.
Kröpil, P.
Quentin, M.
Kuhlemann, J.
Miese, F.
Heiss, C.c.heiss@surrey.ac.uk
Kelm, M.
Antoch, G.
Lanzman, R.S.
Date : May 2012
DOI : 10.1016/j.crad.2011.10.014
Copyright Disclaimer : Copyright © 2011 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
Depositing User : Diane Maxfield
Date Deposited : 16 Aug 2018 11:48
Last Modified : 16 Aug 2018 11:48
URI: http://epubs.surrey.ac.uk/id/eprint/848976

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800