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A review of treatment options for behavioural manifestations of clinical anxiety as a comorbidity in dogs with idiopathic epilepsy

Watson, F, Rusbridge, Clare, Packer, RMA, Casey, RA, Heath, S and Volk, HA (2018) A review of treatment options for behavioural manifestations of clinical anxiety as a comorbidity in dogs with idiopathic epilepsy The Veterinary Journal, 238. pp. 1-9.

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Abstract

Psychiatric comorbidities affect a large percentage of people with epilepsy and have a detrimental impact on their quality of life. Recently, behavioural comorbidities, with similar characteristics to human psychiatric diseases, have been identified in dogs with idiopathic epilepsy. In particular, behaviours motivated by the fear–anxiety emotional system have been found to be associated with the occurrence of idiopathic epilepsy in both dogs receiving anti-epileptic drugs, and drug-naïve dogs. There has been little research into the relationship between epilepsy and behavioural signs, and even less into potential treatment protocols. The following article will review available literature from human medicine to describe the current state of knowledge about the bi-directional relationship between anxiety and epilepsy, draw parallels from reported anxiogenic and anxiolytic properties of anti-epileptic drugs and attempt to provide pharmaceutical and behavioural guidance for veterinary patients with epilepsy and comorbid anxiety.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Veterinary Medicine
Authors :
NameEmailORCID
Watson, F
Rusbridge, Clarec.rusbridge@surrey.ac.uk
Packer, RMA
Casey, RA
Heath, S
Volk, HA
Date : 7 June 2018
DOI : 10.1016/j.tvjl.2018.06.001
Uncontrolled Keywords : Anxiety; Canine behaviour; Dog; Idiopathic epilepsy; Psychiatric comorbidity
Depositing User : Melanie Hughes
Date Deposited : 14 Aug 2018 10:35
Last Modified : 14 Aug 2018 10:35
URI: http://epubs.surrey.ac.uk/id/eprint/848920

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