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Scaling of the corpus callosum in wild and domestic canids: Insights into the domesticated brain.

Spocter, Muhammad A, Uddin, Ashraf, Ng, Johnny C, Wong, Edmund, Wang, Victoria X, Tang, Cheuk, Wicinski, Bridget, Haas, Jordan, Bitterman, Kathleen, Raghanti, Mary Ann , Dunn, Rachel, Hof, Patrick R, Sherwood, Chet C, Jovanovik, Jelena, Rusbridge, Clare and Manger, Paul R (2018) Scaling of the corpus callosum in wild and domestic canids: Insights into the domesticated brain. JOURNAL OF COMPARATIVE NEUROLOGY, 526 (15). pp. 2341-2359.

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Abstract

All domesticated mammals exhibit marked reductions in overall brain size, however, it is unknown whether the corpus callosum, an integral white matter fiber pathway for interhemispheric cortical communication, is affected by domestication differentially or strictly in coordination with changes in brain size. To answer this question, we used quantitative magnetic resonance imaging to compare the mid‐sagittal cross‐sectional areas of the corpus callosum in 35 carnivore species, including eight wild canids and 13 domestic dogs. We segmented rostro‐caudal regions of interest for the corpus callosum and evaluated correlations with brain mass. The results of this study indicate that under the influence of domestication in canids, the corpus callosum scales to brain size in an allometric relationship that is similar to that of wild canids and other carnivores, with relatively high correlation coefficients observed for all regions, except the rostrum. These results indicate that architectural and energetic considerations are likely to tightly constrain variation in caudal components of the corpus callosum relative to overall brain size, however fibers passing through the rostrum, putatively connecting prefrontal cortex, are less constrained and therefore may contribute more towards species‐specific differences in connectivity. Given the species diversity of the Canidae and the resurgence of interest in the brain of the domestic dog, further studies aimed at characterizing the neural architecture in domesticated species is likely to provide new insights into the effects of domestication, or artificial selection, on the brain.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Veterinary Medicine
Authors :
NameEmailORCID
Spocter, Muhammad A
Uddin, Ashraf
Ng, Johnny C
Wong, Edmund
Wang, Victoria X
Tang, Cheuk
Wicinski, Bridget
Haas, Jordan
Bitterman, Kathleen
Raghanti, Mary Ann
Dunn, Rachel
Hof, Patrick R
Sherwood, Chet C
Jovanovik, Jelena
Rusbridge, Clarec.rusbridge@surrey.ac.uk
Manger, Paul R
Date : 19 July 2018
DOI : 10.1002/cne.24486
Copyright Disclaimer : © 2018 Wiley Periodicals, Inc. This is the peer reviewed version of the following article: doi: 10.1002/cne.24486. which will be published in final form at https://onlinelibrary.wiley.com/doi/abs/10.1002/cne.24486. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Depositing User : Melanie Hughes
Date Deposited : 14 Aug 2018 09:39
Last Modified : 20 Jul 2019 02:08
URI: http://epubs.surrey.ac.uk/id/eprint/848918

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