University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Studies in optical activity the rotary powers and dispersions of 2-thienylmethyl and alpha-picolylmethyl carbinols.

Anderson, I. G. (1948) Studies in optical activity the rotary powers and dispersions of 2-thienylmethyl and alpha-picolylmethyl carbinols. Doctoral thesis, University of Surrey (United Kingdom)..

[img]
Preview
Text
10803914.pdf
Available under License Creative Commons Attribution Non-commercial Share Alike.

Download (17MB) | Preview

Abstract

1) Theories of the nature of optical rotatory power are reviewed, with special reference to that of Kuhn. The phenomena of optical rotatory dispersion and corralation between molecular structure and optical rotatory power from ultraviolet absorption data are discussed. Analysis of rotatory dispersion data on the basis of the Drude equation, and some effects of temperature and solvents on rotatory power are reviewed. 2) The preparation of d1 2-thienyl-methyl carbinol is described, and its resolution as the brucine salt of its hydrogen phthalic ester. The rotatory dispersions of the optically active alcohol and its solutions in various solvents are recorded, and shown to be simple in the visible spectrum. The dispersions are discussed in relation to the ultraviolet absorption of the alcohol and conclusions are drawn regarding the type of Drude equation that would be required to cover the complete spectrum, and the most likely chromophoric groups in the molecule. Optical data are recorded for the hydrogen phthalic ester, and alkyl-oxygen fission in this compound has been demonstrated. 3) The preparation of d1 apicolyl-methylcarbinol and a method for its resolution as the brucine salt of its hydrogen phthalic ester are described. The rotatory dispersion of the active alcohol in twelve solvents has been examined in the visible spectrum and found to be simple in associating solvents, but complex and anomalous in non-polar media. The dispersive powers of the hydrogen phthalic and acetate esters and of the p-xenyl urethane are also recorded. A possible explanation of the dispersion phenomena in different solvents and the types of Drude equation required to predict the dispersions are discussed in relation to the ultraviolet absorption of the alcohol.

Item Type: Thesis (Doctoral)
Divisions : Theses
Authors :
NameEmailORCID
Anderson, I. G.
Date : 1948
Contributors :
ContributionNameEmailORCID
http://www.loc.gov/loc.terms/relators/THS
Additional Information : Thesis (Ph.D.)--University of Surrey (United Kingdom), 1948.
Depositing User : EPrints Services
Date Deposited : 22 Jun 2018 15:16
Last Modified : 06 Nov 2018 16:54
URI: http://epubs.surrey.ac.uk/id/eprint/848379

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800