University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Investigation of Synthetic Routes Leading to Vinylphenylhydrazines and Vinylheterocycles.

Schaffer, Rupert Edward. (1958) Investigation of Synthetic Routes Leading to Vinylphenylhydrazines and Vinylheterocycles. Doctoral thesis, University of Surrey (United Kingdom)..

[img]
Preview
Text
10803854.pdf
Available under License Creative Commons Attribution Non-commercial Share Alike.

Download (5MB) | Preview

Abstract

With the object of assessing projected syntheses of vinylheterocycles from hydrazinostyrenes, the uses of arylhydrazines in heterocyclic synthesis and methods of preparation of substituted styrenes and arylhydrazines, are reviewed. Possible synthetic routes to a hydrazinostyrene, taking into account the high reactivity of both substituents, and the formation of polymeric vinylheterocycles from the hydrazinostyrene, are then discussed. Attempts to prepare m-hydrazinostyrene are described, in which m-andnocinnamic acid was diazotised, and reduced to m-hydrazinocinnamic acid various procedures were investigated, but the amphoteric nature of the compounds rendered manipulation somewhat difficult. Attention was then turned to the formation of vinylheterocycles by decarboxylation of beta-(heterocyclic)-acrylic acids, and beta-(4-quinolyl)-acrylic acid was subjected to several decarboxylation procedures, but the principal product is inferred to have been a poly-4-vinylqiuinoline. m-Hydrazinostyrene was finally prepared by the following routes m-nitroacetophenone was reduced to a-methyl-m-nitrobenzyl alcohol, and the latter was dehydrated with phosphoric acid to m-nitrostyrene; this was then reduced to m-aminostyrene, diazotisation of which, and reduction with stannous chloride, yielded m-hydrazinostyrene.

Item Type: Thesis (Doctoral)
Divisions : Theses
Authors :
NameEmailORCID
Schaffer, Rupert Edward.
Date : 1958
Contributors :
ContributionNameEmailORCID
http://www.loc.gov/loc.terms/relators/THS
Additional Information : Thesis (Ph.D.)--University of Surrey (United Kingdom), 1958.
Depositing User : EPrints Services
Date Deposited : 22 Jun 2018 15:15
Last Modified : 06 Nov 2018 16:54
URI: http://epubs.surrey.ac.uk/id/eprint/848321

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800