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In vivo size and shape measurement of the human upper airway using endoscopie long-range optical coherence tomography

Armstrong, J.J., Leigh, M.S., Walton, I.D., Zvyagin, A.V., Alexandrov, S.A., Schwer, S., Sampson, David, Hillman, D.R. and Eastwood, P.R. (2003) In vivo size and shape measurement of the human upper airway using endoscopie long-range optical coherence tomography Optics Express, 11 (15). pp. 1817-1826.

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Abstract

We describe a long-range optical coherence tomography system for size and shape measurement of large hollow organs in the human body. The system employs a frequency-domain optical delay line of a configuration that enables the combination of high-speed operation with long scan range. We compare the achievable maximum delay of several delay line configurations, and identify the configurations with the greatest delay range. We demonstrate the use of one such long-range delay line in a catheter-based optical coherence tomography system and present profiles of the human upper airway and esophagus in vivo with a radial scan range of 26 millimeters. Such quantitative upper airway profiling should prove valuable in investigating the pathophysiology of airway collapse during sleep (obstructive sleep apnea).

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
NameEmailORCID
Armstrong, J.J.
Leigh, M.S.
Walton, I.D.
Zvyagin, A.V.
Alexandrov, S.A.
Schwer, S.
Sampson, Davidd.sampson@surrey.ac.uk
Hillman, D.R.
Eastwood, P.R.
Date : 2003
DOI : 10.1364/OE.11.001817
Uncontrolled Keywords : Biological organs, Endoscopy, Frequency domain analysis, Magnetic resonance imaging, Medical imaging, Optical systems, Pathology, Physiology, Single mode fibers, Endoscopic imaging, Esophagus, Medical and biological imaging, Optical coherence tomography, Tomography
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 12 Jun 2018 10:07
Last Modified : 19 Sep 2018 11:32
URI: http://epubs.surrey.ac.uk/id/eprint/846930

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