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Bifocal optical coherence refractometry of turbid media

Alexandrov, S.A., Zvyagin, A.V., Dilusha Silva, K.K.M.B. and Sampson, David (2003) Bifocal optical coherence refractometry of turbid media Optics Letters, 28 (2). pp. 117-119.

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Abstract

We propose and demonstrate a novel technique, which we term bifocal optical coherence refractometry, for the rapid determination of the refractive index of a turbid medium. The technique is based on the simultaneous creation of two closely spaced confocal gates in a sample. The optical path-length difference between the gates is measured by means of low-coherence interferometry and used to determine the refractive index. We present experimental results for the refractive indices of milk solutions and of human skin in vivo. As the axial scan rate determines the acquisition time, which is potentially of the order of tens of milliseconds, the technique has potential for in vivo refractive-index measurements of turbid biological media under dynamic conditions.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
NameEmailORCID
Alexandrov, S.A.
Zvyagin, A.V.
Dilusha Silva, K.K.M.B.
Sampson, Davidd.sampson@surrey.ac.uk
Date : 2003
DOI : 10.1364/OL.28.000117
Uncontrolled Keywords : Coherent light, Interferometry, Refractive index, Tissue, Tomography, Low coherence interferometry, Turbid media, Refractometers, animal, article, chemistry, equipment design, histology, human, instrumentation, methodology, milk, optics, refractometry, skin, theoretical model, thumb, Animals, Equipment Design, Humans, Milk, Models, Theoretical, Optics, Refractometry, Skin, Thumb
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 11 Jun 2018 09:15
Last Modified : 19 Sep 2018 11:32
URI: http://epubs.surrey.ac.uk/id/eprint/846927

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