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Speckle reduction in optical coherence tomography images using tissue viscoelasticity

Kennedy, B.F., Curatolo, A., Hillman, T.R., Saunders, C.M. and Sampson, D.D. (2011) Speckle reduction in optical coherence tomography images using tissue viscoelasticity Journal of Biomedical Optics, 16 (2).

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We present a technique to reduce speckle in optical coherence tomography images of soft tissues. An average is formed over a set of B-scans that have been decorrelated by viscoelastic creep strain. The necessary correction for the deformation-induced spatial distortions between B-scans is achieved through geometrical co-registration using an affine transformation. Speckle reduction by up to a factor of 1.65 is shown in images of tissue-mimicking soft fibrin phantoms and excised human lymph node tissue with no observable loss of spatial resolution.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
Kennedy, B.F.
Curatolo, A.
Hillman, T.R.
Saunders, C.M.
Date : 2011
DOI : 10.1117/1.3548239
Uncontrolled Keywords : Optical coherence tomography, Speckle reduction, Viscoelasticity, Affine transformations, Coregistration, Lymph node tissues, Soft tissue, Spatial distortion, Spatial resolution, Speckle reduction, Viscoelastic creep, Elasticity, Tissue, Tomography, Viscoelasticity, Viscosity, Speckle, artifact, computer assisted diagnosis, human, image enhancement, image quality, instrumentation, letter, methodology, optical coherence tomography, physiology, reproducibility, sensitivity and specificity, viscosity, Young modulus, Artifacts, Elastic Modulus, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Phantoms, Imaging, Reproducibility of Results, Sensitivity and Specificity, Tomography, Optical Coherence, Viscosity
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 05 Jun 2018 15:29
Last Modified : 19 Sep 2018 11:32

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