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Reduction of image artifacts in three-dimensional optical coherence tomography of skin in vivo

Liew, Y.M., McLaughlin, R.A., Wood, F.M. and Sampson, D.D. (2011) Reduction of image artifacts in three-dimensional optical coherence tomography of skin in vivo Journal of Biomedical Optics, 16 (11).

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This paper presents results of in vivo studies on the effect of refractive index-matching media on image artifacts in optical coherence tomography (OCT) images of human skin. These artifacts present as streaks of artificially low backscatter and displacement or distortion of features. They are primarily caused by refraction and scattering of the OCT light beam at the skin surface. The impact of the application of glycerol and ultrasound gel is assessed on both novel skin-mimicking phantoms and in vivo human skin, including assessment of the epidermal thickening caused by the media. Based on our findings, recommendations are given for optimal OCT imaging of skin in vivo.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
Liew, Y.M.
McLaughlin, R.A.
Wood, F.M.
Date : 2011
DOI : 10.1117/1.3652710
Uncontrolled Keywords : Artifact reduction, Epidermal swelling, Image artifacts, In vivo imaging, OCT, Optical coherence tomography, Refractive-index matching, Skin, glycerol, adult, article, artifact, chemistry, drug effect, epidermis, female, histology, human, image processing, image quality, male, methodology, optical coherence tomography, refractometry, skin, Adult, Artifacts, Epidermis, Female, Glycerol, Humans, Image Processing, Computer-Assisted, Male, Phantoms, Imaging, Refractometry, Skin, Tomography, Optical Coherence
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 05 Jun 2018 15:58
Last Modified : 19 Sep 2018 11:32

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