University of Surrey

Test tubes in the lab Research in the ATI Dance Research

In situ 3D imaging of alveoli with a 30 gauge side-facing optical needle probe

Yang, X., McLaughlin, R.A., Lorenser, D., Kirk, R.W., Noble, P.B. and Sampson, D.D. (2011) In situ 3D imaging of alveoli with a 30 gauge side-facing optical needle probe

Full text not available from this repository.

Abstract

In situ imaging of alveoli and small airways with optical coherence tomography (OCT) needle probes has significant potential in the study and clinical assessment of lung disease. We present the smallest reported OCT needle probe capable of acquiring 3D volumetric data. The side-facing needle probe comprises miniaturized focusing optics consisting of no-core and GRIN fibre, terminated with a reflection-coated, fibre tip beam deflector. The optics are encased within a 30-gauge (outer diameter 310 m) needle, and interfaced to a spectral-domain OCT scanner. Multiple 3D-OCT data sets were acquired on preterm lamb lungs (excised) filled with amniotic fluid and saline. Results demonstrated the ability of such a probe to image individual alveoli and bronchioles, and enabled the rendering of 3D volumetric visualisations of the data. We observed notably less tissue distortion than in earlier work with larger 23 gauge needle probes.

Item Type: Conference or Workshop Item (UNSPECIFIED)
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
NameEmailORCID
Yang, X.
McLaughlin, R.A.
Lorenser, D.
Kirk, R.W.
Noble, P.B.
Sampson, D.D.d.sampson@surrey.ac.uk
Date : 2011
DOI : 10.1109/ISSNIP.2011.6146625
Uncontrolled Keywords : 3D imaging, Amniotic fluid, Beam deflectors, Clinical assessments, Data sets, Fibre tip, Focusing optics, In-situ, Needle probes, Outer diameters, Small airways, Spectral-domain, Volumetric data, Data processing, Gages, Intelligent control, Needles, Optical tomography, Probes, Sensor networks, Smart sensors, Three dimensional computer graphics, Tissue, Visualization, Volumetric analysis, Three dimensional
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 06 Jun 2018 11:05
Last Modified : 19 Sep 2018 11:32
URI: http://epubs.surrey.ac.uk/id/eprint/846843

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800