Optical coherence elastography: Strain imaging in tissue using optical coherence tomography

Kennedy, B.F., Kennedy, K.M., Ford, C., McLaughlin, R.A., Bush, M.B. and Sampson, D.D. (2012) Optical coherence elastography: Strain imaging in tissue using optical coherence tomography

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Abstract

Optical coherence elastography (OCE) is a strain imaging technique that characterizes the elastic properties of tissues with microscopic resolution in three dimensions. In OCE, the displacement introduced to tissue by mechanical excitation is measured using optical coherence tomography. The local strain is calculated from the spatial derivative of displacement to generate strain images, known as elastograms. To validate elastograms, we compare them to a finite element analysis model of sample deformation. We also present preliminary OCE measurements performed on excised human breast tissue, and demonstrate discrimination of tissue types based on their elastic properties.

Item Type:	Conference or Workshop Item (UNSPECIFIED)
Divisions :	Faculty of Engineering and Physical Sciences Faculty of Health and Medical Sciences
Authors :	Name Email ORCID Kennedy, B.F. Kennedy, K.M. Ford, C. McLaughlin, R.A. Bush, M.B. Sampson, D.D. d.sampson@surrey.ac.uk
Date :	2012
DOI :	10.1117/12.975187
Uncontrolled Keywords :	Elastogram, Elastography, Finite element analysis, Optical coherence tomography, Strain, Elastograms, Elastography, Finite element analysis model, Human breast tissue, Mechanical excitations, Microscopic resolution, Optical coherence elastography, Spatial derivatives, Elasticity, Finite element method, Medical imaging, Optical tomography, Strain, Tissue
Depositing User :	Maria Rodriguez-Marquez
Date Deposited :	05 Jun 2018 14:26
Last Modified :	19 Sep 2018 11:32
URI:	http://epubs.surrey.ac.uk/id/eprint/846829

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