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Optical palpation in vivo: Imaging human skin lesions using mechanical contrast

Es'Haghian, S., Kennedy, K.M., Gong, P., Sampson, David, McLaughlin, R.A. and Kennedy, B.F. (2015) Optical palpation in vivo: Imaging human skin lesions using mechanical contrast Journal of Biomedical Optics, 20 (1).

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We demonstrate the first application of the recently proposed method of optical palpation to in vivo imaging of human skin. Optical palpation is a tactile imaging technique that probes the spatial variation of a sample's mechanical properties by producing an en face map of stress measured at the sample surface. This map is determined from the thickness of a translucent, compliant stress sensor placed between a loading element and the sample and is measured using optical coherence tomography. We assess the performance of optical palpation using a handheld imaging probe on skin-mimicking phantoms, and demonstrate its use on human skin lesions. Our results demonstrate the capacity of optical palpation to delineate the boundaries of lesions and to map the mechanical contrast between lesions and the surrounding normal skin.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
Es'Haghian, S.
Kennedy, K.M.
Gong, P.
McLaughlin, R.A.
Kennedy, B.F.
Date : 2015
DOI : 10.1117/1.JBO.20.1.016013
Uncontrolled Keywords : biomechanics, optical coherence elastography, optical coherence tomography, optical palpation, scar, skin, skin lesion, tactile imaging, Biomechanics, Dermatology, Imaging techniques, Mechanical properties, Medical imaging, Optical tomography, Probes, Skin, Stress analysis, Tomography, Imaging probe, In-Vivo imaging, Optical coherence elastography, optical palpation, Sample surface, scar, Skin lesion, Spatial variations, Stresses, adult, biomechanics, elastography, female, functions of the skin and its appendages, human, imaging phantom, male, optical coherence tomography, pathophysiology, physiology, procedures, scar, skin tumor, Adult, Biomechanical Phenomena, Cicatrix, Elasticity Imaging Techniques, Female, Humans, Male, Phantoms, Imaging, Skin Neoplasms, Skin Physiological Phenomena, Tomography, Optical Coherence
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 04 Jun 2018 10:04
Last Modified : 19 Sep 2018 11:32

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