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Ultrahigh-resolution optical coherence elastography

Curatolo, A., Villiger, M., Lorenser, D., Wijesinghe, P., Fritz, A., Kennedy, B.F. and Sampson, David (2016) Ultrahigh-resolution optical coherence elastography Optics Letters, 41 (1). pp. 21-24.

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Abstract

Visualizing stiffness within the local tissue environment at the cellular and subcellular level promises to provide insight into the genesis and progression of disease. In this Letter, we propose ultrahigh-resolution optical coherence elastography (UHROCE), and demonstrate 3D imaging of local axial strain of tissues undergoing compressive loading. We combine optical coherence microscopy (OCM) and phase-sensitive detection of local tissue displacement to produce strain elastograms with resolution (

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
NameEmailORCID
Curatolo, A.
Villiger, M.
Lorenser, D.
Wijesinghe, P.
Fritz, A.
Kennedy, B.F.
Sampson, Davidd.sampson@surrey.ac.uk
Date : 2016
DOI : 10.1364/OL.41.000021
Uncontrolled Keywords : Tissue, Compressive loading, Mechanical heterogeneity, Optical coherence elastography, Optical coherence microscopy, Phase-sensitive detection, Tissue displacement, Ultrahigh resolution, Vascular Smooth Muscle Cells, Medical imaging, animal, aorta, echography, elastography, imaging phantom, mouse, optical coherence tomography, procedures, signal noise ratio, three dimensional imaging, Animals, Aorta, Elasticity Imaging Techniques, Imaging, Three-Dimensional, Mice, Phantoms, Imaging, Signal-To-Noise Ratio, Tomography, Optical Coherence
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 04 Jun 2018 09:12
Last Modified : 19 Sep 2018 11:32
URI: http://epubs.surrey.ac.uk/id/eprint/846770

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