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The emergence of optical elastography in biomedicine

Kennedy, B.F., Wijesinghe, P. and Sampson, David (2017) The emergence of optical elastography in biomedicine Nature Photonics, 11 (4). pp. 215-221.

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Abstract

Optical elastography, the use of optics to characterize and map the mechanical properties of biological tissue, involves measuring the deformation of tissue in response to a load. Such measurements may be used to form an image of a mechanical property, often elastic modulus, with the resulting mechanical contrast complementary to the more familiar optical contrast. Optical elastography is experiencing new impetus in response to developments in the closely related fields of cell mechanics and medical imaging, aided by advances in photonics technology, and through probing the microscale between that of cells and whole tissues. Two techniques — optical coherence elastography and Brillouin microscopy — have recently shown particular promise for medical applications, such as in ophthalmology and oncology, and as new techniques in cell mechanics.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
NameEmailORCID
Kennedy, B.F.
Wijesinghe, P.
Sampson, Davidd.sampson@surrey.ac.uk
Date : 2017
DOI : 10.1038/nphoton.2017.6
Uncontrolled Keywords : Biomechanics, Mechanical properties, Medical applications, Tissue, Biological tissues, Brillouin microscopy, Cell mechanics, Optical coherence elastography, Optical contrast, Optical elastography, Photonics technology, Medical imaging
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 04 Jun 2018 08:20
Last Modified : 19 Sep 2018 11:32
URI: http://epubs.surrey.ac.uk/id/eprint/846738

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