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Flexible needle with integrated optical coherence tomography probe for imaging during transbronchial tissue aspiration

Li, J., Quirk, B.C., Noble, P.B., Kirk, R.W., Sampson, David and McLaughlin, R.A. (2017) Flexible needle with integrated optical coherence tomography probe for imaging during transbronchial tissue aspiration Journal of Biomedical Optics, 22 (10).

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Abstract

Transbronchial needle aspiration (TBNA) of small lesions or lymph nodes in the lung may result in nondiagnostic tissue samples. We demonstrate the integration of an optical coherence tomography (OCT) probe into a 19-gauge flexible needle for lung tissue aspiration. This probe allows simultaneous visualization and aspiration of the tissue. By eliminating the need for insertion and withdrawal of a separate imaging probe, this integrated design minimizes the risk of dislodging the needle from the lesion prior to aspiration and may facilitate more accurate placement of the needle. Results from in situ imaging in a sheep lung show clear distinction between solid tissue and two typical constituents of nondiagnostic samples (adipose and lung parenchyma). Clinical translation of this OCT-guided aspiration needle holds promise for improving the diagnostic yield of TBNA.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
NameEmailORCID
Li, J.
Quirk, B.C.
Noble, P.B.
Kirk, R.W.
Sampson, Davidd.sampson@surrey.ac.uk
McLaughlin, R.A.
Date : 2017
DOI : 10.1117/1.JBO.22.10.106002
Uncontrolled Keywords : biopsy guidance, endoscopic imaging, fiber-optic imaging, optical coherence tomography, Biological organs, Needles, Optical tomography, Probes, Tomography, Biopsy guidance, Clinical translation, Endoscopic imaging, Fiber-optic imaging, Flexible needle, Integrated designs, Optical coherence tomography probes, Transbronchial needle aspirations, Tissue
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 04 Jun 2018 08:24
Last Modified : 19 Sep 2018 11:32
URI: http://epubs.surrey.ac.uk/id/eprint/846732

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