Human Trichuriasis: Whipworm Genetics, Phylogeny, Transmission and Future Research Directions

Betson, Martha, Søe, Martin Jensen and Nejsum, Peter (2015) Human Trichuriasis: Whipworm Genetics, Phylogeny, Transmission and Future Research Directions Current Tropical Medicine Reports, 2 (4). pp. 209-217.

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Abstract

Human trichuriasis is a neglected tropical disease which affects hundreds of millions of people worldwide and is particularly prevalent among children living in areas where sanitation is poor. This review examines the current knowledge on the taxonomy, genetics and phylogeography of human Trichuris and its relationship to whipworm parasites in other host species. The evidence for zoonotic transmission of Trichuris and the emergence of anthelmintic resistance is assessed. In addition, the implications of the recent publication of the genomes and transcriptomes of multiple Trichuris species are discussed. Finally, priorities for future research in Trichuris genetics are proposed.

Item Type:	Article
Divisions :	Faculty of Health and Medical Sciences > School of Veterinary Medicine
Authors :	Name Email ORCID Betson, Martha m.betson@surrey.ac.uk Søe, Martin Jensen Nejsum, Peter
Date :	2015
DOI :	10.1007/s40475-015-0062-y
Copyright Disclaimer :	© Springer International Publishing AG 2015
Uncontrolled Keywords :	Trichuris; Whipworm; Phylogenetics; Genomics; Ancient DNA; Soil-transmitted helminth; Zoonosis; Anthelmintic resistance
Depositing User :	Clive Harris
Date Deposited :	10 May 2018 10:06
Last Modified :	16 Jan 2019 19:09
URI:	http://epubs.surrey.ac.uk/id/eprint/846393

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