Human Trichuriasis: Whipworm Genetics, Phylogeny, Transmission and Future Research Directions
Betson, Martha, Søe, Martin Jensen and Nejsum, Peter (2015) Human Trichuriasis: Whipworm Genetics, Phylogeny, Transmission and Future Research Directions Current Tropical Medicine Reports, 2 (4). pp. 209-217.
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Abstract
Human trichuriasis is a neglected tropical disease which affects hundreds of millions of people worldwide and is particularly prevalent among children living in areas where sanitation is poor. This review examines the current knowledge on the taxonomy, genetics and phylogeography of human Trichuris and its relationship to whipworm parasites in other host species. The evidence for zoonotic transmission of Trichuris and the emergence of anthelmintic resistance is assessed. In addition, the implications of the recent publication of the genomes and transcriptomes of multiple Trichuris species are discussed. Finally, priorities for future research in Trichuris genetics are proposed.
Item Type: | Article | ||||||||||||
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Divisions : | Faculty of Health and Medical Sciences > School of Veterinary Medicine | ||||||||||||
Authors : |
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Date : | 2015 | ||||||||||||
DOI : | 10.1007/s40475-015-0062-y | ||||||||||||
Copyright Disclaimer : | © Springer International Publishing AG 2015 | ||||||||||||
Uncontrolled Keywords : | Trichuris; Whipworm; Phylogenetics; Genomics; Ancient DNA; Soil-transmitted helminth; Zoonosis; Anthelmintic resistance | ||||||||||||
Depositing User : | Clive Harris | ||||||||||||
Date Deposited : | 10 May 2018 10:06 | ||||||||||||
Last Modified : | 16 Jan 2019 19:09 | ||||||||||||
URI: | http://epubs.surrey.ac.uk/id/eprint/846393 |
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