University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Oleanane Triterpenoids from the Algerian Salvia phlomoides

Benniou, L, Langat, Moses, Mulholland, Dulcie, Benayache, F and Benayache, S (2018) Oleanane Triterpenoids from the Algerian Salvia phlomoides Phytochemistry Letters.

[img] Text
Oleanane Triterpenoids from the Algerian Salvia phlomoides.docx - Accepted version Manuscript
Restricted to Repository staff only

Download (68kB)

Abstract

Three previously unreported triterpenoids 2α,3β,11α-trihydroxyolean-18-ene 1, 3β-acetoxy,2α,11α- dihydroxyolean-18-ene 2 and 2α-acetoxy,3β,11α-dihydroxyolean-18-ene 3 were isolated from the chloroform extract of aerial parts (leaves and flowers) of Salvia phlomoides collected from the Constantine region in the east of Algeria. Structures were determined using NMR spectroscopy and HR-ESI mass spectrometry. Compounds 1, 2 and 3 were tested against the NCI panel of human tumour cell lines at a single dose of 10 µM. Compound 2 was the most active showing a 38 % growth inhibition against the leukemia RPMI-8226 line.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Chemistry
Authors :
NameEmailORCID
Benniou, LUNSPECIFIEDUNSPECIFIED
Langat, MosesM.Langat@surrey.ac.ukUNSPECIFIED
Mulholland, DulcieD.Mulholland@surrey.ac.ukUNSPECIFIED
Benayache, FUNSPECIFIEDUNSPECIFIED
Benayache, SUNSPECIFIEDUNSPECIFIED
Date : 12 May 2018
Copyright Disclaimer : © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Uncontrolled Keywords : Lamiaceae, Salvia phlomoides, oleanane triterpenoids, cytotoxicity screening.
Depositing User : Melanie Hughes
Date Deposited : 12 Feb 2018 11:26
Last Modified : 12 Feb 2018 11:26
URI: http://epubs.surrey.ac.uk/id/eprint/845810

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800