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Physical activity reduces fatigue in patients with cancer and hematopoietic stem cell transplant recipients: A systematic review and meta-analysis of randomized trials

Oberoi, Sapna, Robinson, Paula D., Cataudella, Danielle, Culos-Reid, Nicole, Davis, Hailey, Duong, Nathan, Gibson, Faith, Götte, Miriam, Hinds, Pamela, Nijhof, Sanne L , Tomlinson, Deborah, van der Torre, Patrick, Cabral, Sandra, Dupuis, LLee and Sung, Lillian (2017) Physical activity reduces fatigue in patients with cancer and hematopoietic stem cell transplant recipients: A systematic review and meta-analysis of randomized trials Critical Reviews in Oncology/Hematology.

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Physical activity reduces fatigue in patients with cancer and hematopoietic stem cell transplant recipients - A systematic review and meta-analysis of randomized trials.pdf - Accepted version Manuscript
Restricted to Repository staff only until 16 December 2018.

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Abstract

Purpose Objective was to determine whether physical activity reduces the severity of fatigue in patients with cancer or hematopoietic stem cell transplant (HSCT) recipients. Methods We conducted a meta-analysis of randomized trials comparing physical activity with control interventions for the management of fatigue in patients with cancer or HSCT recipients. Results There were 170 trials included. Physical activity reduced the severity of fatigue when compared to all control groups (standardized mean difference −0.49, 95% confidence interval −0.60 to −0.37; P < 0.00001). Aerobic, neuromotor, resistance and combination exercises were all effective in reducing fatigue although smaller effects were observed with resistance exercises (P interaction = 0.01). Other intervention and patient characteristics did not influence the effect of physical activity on the severity of fatigue. Conclusions Physical activity was effective at reducing fatigue in patients with cancer and HSCT recipients across patient sub-groups. Determining the best approaches for safe implementation should be a priority.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Health Sciences
Authors :
NameEmailORCID
Oberoi, SapnaUNSPECIFIEDUNSPECIFIED
Robinson, Paula D.UNSPECIFIEDUNSPECIFIED
Cataudella, DanielleUNSPECIFIEDUNSPECIFIED
Culos-Reid, NicoleUNSPECIFIEDUNSPECIFIED
Davis, HaileyUNSPECIFIEDUNSPECIFIED
Duong, NathanUNSPECIFIEDUNSPECIFIED
Gibson, Faithf.gibson@surrey.ac.ukUNSPECIFIED
Götte, MiriamUNSPECIFIEDUNSPECIFIED
Hinds, PamelaUNSPECIFIEDUNSPECIFIED
Nijhof, Sanne LUNSPECIFIEDUNSPECIFIED
Tomlinson, DeborahUNSPECIFIEDUNSPECIFIED
van der Torre, PatrickUNSPECIFIEDUNSPECIFIED
Cabral, SandraUNSPECIFIEDUNSPECIFIED
Dupuis, LLeeUNSPECIFIEDUNSPECIFIED
Sung, LillianUNSPECIFIEDUNSPECIFIED
Date : 16 December 2017
Identification Number : 10.1016/j.critrevonc.2017.12.011
Copyright Disclaimer : © 2017 Elsevier Ltd. All rights reserved.
Uncontrolled Keywords : Fatigue; Cancer; Exercise; Physical activity; Randomized trial; Meta-analysis
Depositing User : Clive Harris
Date Deposited : 21 Dec 2017 15:05
Last Modified : 21 Dec 2017 15:05
URI: http://epubs.surrey.ac.uk/id/eprint/845502

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