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What is the evidence for a role for diet and nutrition in osteoarthritis?

Thomas, Sally, Browne, Heather, Mobasheri, Ali and Rayman, Margaret (2017) What is the evidence for a role for diet and nutrition in osteoarthritis? Rheumatology.

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As current treatment options in osteoarthritis are very limited, osteoarthritis patients would benefit greatly from some ability to self-manage their condition. Since diet may potentially affect osteoarthritis, we reviewed the literature on the relationship between nutrition and osteoarthritis risk or progression, aiming to provide guidance for clinicians. For overweight/obese patients, weight-reduction, ideally incorporating exercise, is paramount. The association between metabolic syndrome, type-2 diabetes and osteoarthritis risk or progression may partly explain the apparent benefit of dietary-lipid modification resulting from increased consumption of long-chain n-3 fatty-acids from oily fish/fish-oil supplements. A strong association between osteoarthritis and raised serum cholesterol together with clinical effects in statin users suggest a potential benefit or reduction of cholesterol by dietary means. Patients should ensure that they meet the recommended intakes for micronutrients such as vitamin K which has a role in bone/cartilage mineralization. Evidence for a role of vitamin-D supplementation in osteoarthritis is unconvincing.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Veterinary Medicine
Authors :
Thomas, Sally
Browne, Heather
Date : 2017
Copyright Disclaimer : © 2017 Oxford University Press
Uncontrolled Keywords : Nutrition; Osteoarthritis (OA); Obesity; Diabetes; Metabolic syndrome; Polyunsaturated fatty acids (PUFAs); Cholesterol; Anti-oxidants; Vitamin D; Vitamin K
Depositing User : Clive Harris
Date Deposited : 21 Dec 2017 09:21
Last Modified : 14 Mar 2018 16:01

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