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Pristine carbon nanotube scaffolds for the growth of chondrocytes

King, Alice A. K., Matta-Domjan, Brigitta, Large, Matthew J., Matta, Csaba, Ogilvie, Sean P., Bardi, Niki, Byrne, Hugh J., Zakhidov, Anvar, Jurewicz, Izabela, Velliou, Eirini , Lewis, Rebecca, La Ragione, Roberto and Dalton, Alan (2017) Pristine carbon nanotube scaffolds for the growth of chondrocytes Journal of Materials Chemistry B, 5 (41). pp. 8178-8182.

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The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unreliability of traditional dye based assays for carbon nanomaterial substrates. The textile exhibits a very high affinity for chondrocyte growth and could present a route to implantable, flexible cartilage scaffolds with tuneable mechanical properties.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Physics
Authors :
King, Alice A. K.
Matta-Domjan, Brigitta
Large, Matthew J.
Ogilvie, Sean P.
Byrne, Hugh J.
Zakhidov, Anvar
La Ragione,
Date : 9 October 2017
Funders : Engineering and Physical Sciences Research Council (EPSRC)
Identification Number : 10.1039/C7TB02065A
Copyright Disclaimer : © The Royal Society of Chemistry 2017
Depositing User : Clive Harris
Date Deposited : 14 Nov 2017 11:19
Last Modified : 19 Jun 2018 06:14

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