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Use of an attenuated live Salmonella Typhimurium vaccine on three breeding pig units: A longitudinal observational field study

Davies, R, Gosling, RJ, Wales, Andrew and Smith, RP (2016) Use of an attenuated live Salmonella Typhimurium vaccine on three breeding pig units: A longitudinal observational field study Comparative Immunology, Microbiology and Infectious Diseases, 46. pp. 7-15.

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Abstract

The study examined the effects of a licensed live Salmonella Typhimurium vaccine, administered to sows and gilts on three commercial pig units experiencing clinical salmonellosis associated with S. Typhimurium or its monophasic variant. After vaccination, clinical salmonellosis resolved and shedding of S. Typhimurium declined markedly and persistently on all breeding or breedingfinishing units, during the one- to two-year monitoring period. On two finishing units supplied in part by one of the vaccinated herds, pigs from the vaccinated herd were less likely to shed Salmonella than those from non-vaccinating herds, and Salmonella counts in faeces were also lower from the vaccine-linked animals. Non-Typhimurium Salmonella serovars were isolated typically in fewer than 10% of samples, and showed no clear temporal changes in frequency. Vaccination of dams alone with S. Typhimurium was associated with reduced shedding of closely-related serovars among all age groups in this commercial setting.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Veterinary Medicine
Authors :
NameEmailORCID
Davies, RUNSPECIFIEDUNSPECIFIED
Gosling, RJUNSPECIFIEDUNSPECIFIED
Wales, Andrewaw0051@surrey.ac.uk0000-0002-8657-3007
Smith, RPUNSPECIFIEDUNSPECIFIED
Date : 24 March 2016
Identification Number : 10.1016/j.cimid.2016.03.005
Copyright Disclaimer : © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Uncontrolled Keywords : Salmonella, Typhimurium, vaccine, pig, swine
Depositing User : Melanie Hughes
Date Deposited : 18 Oct 2017 15:41
Last Modified : 24 Oct 2017 12:06
URI: http://epubs.surrey.ac.uk/id/eprint/842573

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