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Pristine carbon nanotube scaffolds for the growth of chondrocytes

King, Alice, Matta-Domjan, Brigitta, Large, Matthiew J, Matta, Csaba, Ogilvie, Sean Paul, Bardi, Niki, Byrne, Hugh, Zakhidov, A, Jurewicz, Isabela, Velliou, Eirini , Lewis, Rebecca, LaRagione, Roberto and Dalton, Alan B (2017) Pristine carbon nanotube scaffolds for the growth of chondrocytes Journal of Materials Chemistry B.

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Abstract

The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unreliability of traditional dye based assays for carbon nanomaterial substrates. The textile exhibits a very high affinity for chondrocyte growth and could present a route to implantable, flexible cartilage scaffolds with tuneable mechanical properties.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Chemical and Process Engineering
Authors :
NameEmailORCID
King, AliceUNSPECIFIEDUNSPECIFIED
Matta-Domjan, BrigittaUNSPECIFIEDUNSPECIFIED
Large, Matthiew JUNSPECIFIEDUNSPECIFIED
Matta, CsabaUNSPECIFIEDUNSPECIFIED
Ogilvie, Sean PaulUNSPECIFIEDUNSPECIFIED
Bardi, NikiUNSPECIFIEDUNSPECIFIED
Byrne, HughUNSPECIFIEDUNSPECIFIED
Zakhidov, AUNSPECIFIEDUNSPECIFIED
Jurewicz, IsabelaUNSPECIFIEDUNSPECIFIED
Velliou, Eirinie.velliou@surrey.ac.ukUNSPECIFIED
Lewis, RebeccaUNSPECIFIEDUNSPECIFIED
LaRagione, RobertoUNSPECIFIEDUNSPECIFIED
Dalton, Alan BUNSPECIFIEDUNSPECIFIED
Date : 9 October 2017
Funders : Engineering and Physical Sciences Research Council (EPSRC)
Identification Number : 10.1039/c7tb02065a
Copyright Disclaimer : © The Royal Society of Chemistry 2017
Depositing User : Clive Harris
Date Deposited : 12 Oct 2017 12:40
Last Modified : 12 Oct 2017 12:40
URI: http://epubs.surrey.ac.uk/id/eprint/842532

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