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Efficacy of extracts from eight economically important forestry species against grapevine downy mildew (Plasmopara viticola) and identification of active constituents.

Mulholland, Dulcie, Thuerig, B, Langat, Moses, Tamm, L, Nawrot, DA, James, Emily, Qayyum, M, Shen, D, Ennis, K, Jones, A , Hokkanen, H, Demidova, N, Izotove, D and Schärer, H-J (2017) Efficacy of extracts from eight economically important forestry species against grapevine downy mildew (Plasmopara viticola) and identification of active constituents. Crop Protection.

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Abstract

Downy mildew caused by the oomycete Plasmopara viticola is the most devastating pathogen of grapevine. In this study, extracts of the bark of eight important northern forestry species were screened to find extracts showing activity against this pathogen and to identify the active compounds. Extracts from all eight species showed activity against P. viticola, the most promising, dichloromethane extracts of three Larix species, almost completely protecting grapevine from downy mildew under semi-controlled conditions. Five promising lead compounds were isolated: larixol, larixyl acetate, lariciresinol and lariciresinol acetate from Larix species and 7α,15-dihydroxydehydroabietic acid from Pinus sylvestris. These compounds showed 90%-100% efficacy. Larixol and larixyl acetate or 7α,15-dihydroxydehydroabietic acid are present in significant amounts in Larix or P. sylvestris bark extracts, respectively. The identified active compounds are gained from a renewable resource potentially available in large quantities at relatively low prices, making them interesting candidates for the development of a plant-derived fungicide active against a key pathogen in agriculture, providing an opportunity to the forest industry to transform low value by-products into high value-added, bioactive extracts.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Chemistry
Authors :
NameEmailORCID
Mulholland, DulcieD.Mulholland@surrey.ac.ukUNSPECIFIED
Thuerig, BUNSPECIFIEDUNSPECIFIED
Langat, MosesM.Langat@surrey.ac.ukUNSPECIFIED
Tamm, LUNSPECIFIEDUNSPECIFIED
Nawrot, DAUNSPECIFIEDUNSPECIFIED
James, Emilye.e.james@surrey.ac.ukUNSPECIFIED
Qayyum, MUNSPECIFIEDUNSPECIFIED
Shen, DUNSPECIFIEDUNSPECIFIED
Ennis, KUNSPECIFIEDUNSPECIFIED
Jones, AUNSPECIFIEDUNSPECIFIED
Hokkanen, HUNSPECIFIEDUNSPECIFIED
Demidova, NUNSPECIFIEDUNSPECIFIED
Izotove, DUNSPECIFIEDUNSPECIFIED
Schärer, H-JUNSPECIFIEDUNSPECIFIED
Date : 25 November 2017
Copyright Disclaimer : © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Uncontrolled Keywords : Fungicide, Plasmopara viticola, Larix, Pinus sylvestris, Larixol, Larixyl acetate
Depositing User : Melanie Hughes
Date Deposited : 25 Aug 2017 12:25
Last Modified : 25 Aug 2017 12:25
URI: http://epubs.surrey.ac.uk/id/eprint/842048

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