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Alginate electrodeposition onto three-dimensional porous Co-Ni films as drug delivery platforms.

García-Torres, J, Gispert, C, Gómez, E and Vallés, E (2015) Alginate electrodeposition onto three-dimensional porous Co-Ni films as drug delivery platforms. Phys Chem Chem Phys, 17 (3). pp. 1630-1636.

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Three-dimensional porous Co-Ni films/alginate hybrid materials have been successfully prepared by electrodeposition to be used as a steerable magnetic device for drug delivery. Firstly, 3D porous Co-Ni films were prepared as substrates for the subsequent electrodeposition of the alginate biopolymer. Cyclic voltammetry, galvanostatic and potentiostatic studies were performed to establish the best conditions to obtain porous Co-Ni films. The electrochemical experiments were carried out in an electrolyte containing the metal salts and ammonium chloride at low pHs. In a second stage, the electrochemical deposition of alginate as a biocompatible polymer drug delivery carrier was performed. The characteristics of the alginate matrix were investigated in terms of electrochemical properties, morphology and drug release. The hybrid material obtained showed soft-magnetic behavior and drug release indicating its suitability to be used as a steerable magnetic drug delivery device.

Item Type: Article
Authors :
García-Torres, J
Gispert, C
Gómez, E
Vallés, E
Date : 21 January 2015
DOI : 10.1039/c4cp04389h
Uncontrolled Keywords : Alginates, Cobalt, Drug Delivery Systems, Electroplating, Glucuronic Acid, Hemoglobins, Hexuronic Acids, Microscopy, Electron, Scanning, Nickel, Porosity, Surface Properties
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 13:31
Last Modified : 17 May 2017 13:31

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