University of Surrey

Test tubes in the lab Research in the ATI Dance Research

A bio-analytical system for rapid cellular electrophysiological assays.

Fatoyinbo, HO, Gould, DH and Labeed, FH (2010) A bio-analytical system for rapid cellular electrophysiological assays. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. pp. 6510-6513.

Full text not available from this repository.

Abstract

In this paper, the use of non-uniform ac electric fields on biological cells for bioanalysis, through multiple, independently configurable channels is presented. The programmable system has been used to obtain the dielectrophoretic spectra of cells in near real time, within 90 seconds. This is a significant improvement on existing dielectrophoretic techniques as simultaneous parallel measurement of the dielectrophoretic forces at different frequencies has potential of revealing subtle changes to the electrophysiology of cells, as they occur. The results show that with continuous on-chip monitoring, cells exposed to a chemical agent that induces apoptosis begin to exhibit a spectrum that differs from untreated cells, as indicated from shifts in the observed crossover frequency values.

Item Type: Article
Authors :
NameEmailORCID
Fatoyinbo, HOUNSPECIFIEDUNSPECIFIED
Gould, DHUNSPECIFIEDUNSPECIFIED
Labeed, FHf.labeed@surrey.ac.ukUNSPECIFIED
Date : 1 December 2010
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 13:18
Last Modified : 17 May 2017 15:10
URI: http://epubs.surrey.ac.uk/id/eprint/838717

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800