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Isoeugenitol, a cyclooxygenase-1 inhibitor from Gethyllis ciliaris

Elgorashi, EE, Coombes, PH, Mulholland, DA and Van Staden, J (2007) Isoeugenitol, a cyclooxygenase-1 inhibitor from Gethyllis ciliaris South African Journal of Botany, 73 (1). pp. 156-158.

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Bioassay guided fractionation of the dichloromethane extract of the underground parts of Gethyllis ciliaris, using a cyclooxygenase-1 enzyme assay, has resulted in the isolation of the dihydroxydimethylbenzopyran-4-one isoeugenitol 1 (IC50 = 262 μM). The 90% methanolic extract yielded 9Z-octadec-9-enamide 3 and the novel compound isoeugenitol glycoside 2. The structures of the isolated compounds have been assigned on the basis of spectral analysis, including 1D and 2D NMR techniques. © 2006 Elsevier B.V. All rights reserved.

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Elgorashi, EE
Coombes, PH
Van Staden, J
Date : 1 January 2007
DOI : 10.1016/j.sajb.2006.06.008
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 12:56
Last Modified : 24 Jan 2020 23:08

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