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METAL ION-BIOMOLECULE INTERACTIONS - BINDING OF METHYLMERCURY TO NUCLEOSIDES AND NEUROTOXICOLOGICAL EFFECTS.

Buncel, E, Kumar, R, Norris, AR, Racz, WJ, Taylor, SE and Vandewater, LJS (1983) METAL ION-BIOMOLECULE INTERACTIONS - BINDING OF METHYLMERCURY TO NUCLEOSIDES AND NEUROTOXICOLOGICAL EFFECTS. pp. 609-612.

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Abstract

The interactions of methylmercury (MM) with purine and pyrimidine bases (DNA constituents) have been examined through physico-chemical studies, as tests of the hypothesis that the toxicity of MM could arise through mechanisms alternative to reaction with sulfhydryl and disulfide groups of aminoacids and proteins. We have thus isolated solid CH//3Hg**I**I containing complexes of nucleosides from the interaction with CH//3HgNO//3 in aqueous solution under predetermined conditions of pH and stoichiometry.

Item Type: Article
Authors :
NameEmailORCID
Buncel, EUNSPECIFIEDUNSPECIFIED
Kumar, RUNSPECIFIEDUNSPECIFIED
Norris, ARUNSPECIFIEDUNSPECIFIED
Racz, WJUNSPECIFIEDUNSPECIFIED
Taylor, SEs.taylor@surrey.ac.ukUNSPECIFIED
Vandewater, LJSUNSPECIFIEDUNSPECIFIED
Date : 1 December 1983
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 12:56
Last Modified : 17 May 2017 15:07
URI: http://epubs.surrey.ac.uk/id/eprint/837347

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