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N-Substituted acridone alkaloids from Toddaliopsis bremekampii (Rutaceae: Toddalioideae) of south-central Africa.

Naidoo, D, Coombes, PH, Mulholland, DA, Crouch, NR and van den Bergh, AJ (2005) N-Substituted acridone alkaloids from Toddaliopsis bremekampii (Rutaceae: Toddalioideae) of south-central Africa. Phytochemistry, 66 (14). pp. 1724-1728.

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Abstract

Toddaliopsins A-D, four novel 1,2,3-trioxygenated acridone alkaloids, have been isolated from the leaves of Toddaliopsis bremekampii. Toddaliopsins B-D are the first reported acridone alkaloids with substituted N-methyl groups, in the light of which the chemotaxonomic relationship of Toddaliopsis and Vepris is discussed. Toddaliopsin C possesses moderate anti-inflammatory activity, which may be related to the hydroxy group present at C-1.

Item Type: Article
Authors :
NameEmailORCID
Naidoo, DUNSPECIFIEDUNSPECIFIED
Coombes, PHUNSPECIFIEDUNSPECIFIED
Mulholland, DAd.mulholland@surrey.ac.ukUNSPECIFIED
Crouch, NRUNSPECIFIEDUNSPECIFIED
van den Bergh, AJUNSPECIFIEDUNSPECIFIED
Date : July 2005
Identification Number : 10.1016/j.phytochem.2005.04.036
Uncontrolled Keywords : Acridines, Africa, Alkaloids, Humans, In Vitro Techniques, Luminescent Measurements, Molecular Structure, Neutrophils, Plant Leaves, Rutaceae
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 12:55
Last Modified : 17 May 2017 15:06
URI: http://epubs.surrey.ac.uk/id/eprint/837242

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