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Antiplasmodial diterpenoid from the leaves of Hyptis suaveolens.

Chukwujekwu, JC, Smith, P, Coombes, PH, Mulholland, DA and van Staden, J (2005) Antiplasmodial diterpenoid from the leaves of Hyptis suaveolens. J Ethnopharmacol, 102 (2). pp. 295-297.

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Bioactivity-guided fractionation of the petroleum ether extract of the leaves of Hyptis suaveolens, widely used in Traditional Medicine, has led to the isolation of an abietane-type diterpenoid endoperoxide, 13 alpha-epi-dioxiabiet-8(14)-en-18-ol, displaying high antiplasmodial activity (IC(50) 0.1 microg/ml).

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Chukwujekwu, JC
Smith, P
Coombes, PH
van Staden, J
Date : 14 November 2005
DOI : 10.1016/j.jep.2005.08.018
Uncontrolled Keywords : Animals, Antimalarials, Diterpenes, Hyptis, Plant Leaves, Plasmodium falciparum
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 12:55
Last Modified : 24 Jan 2020 23:05

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