Elemental and structural studies at the bone-cartilage interface
Bradley, DA, Kaabar, W and Gundogdu, O (2012) Elemental and structural studies at the bone-cartilage interface In: IX LATIN AMERICAN SYMPOSIUM ON NUCLEAR PHYSICS AND APPLICATIONS, 2011-07-18 - 2011-07-22, Quito, Ecuador.
Full text not available from this repository.Abstract
The techniques μProton-Induced X-and γ-ray Emission, μ-PIXE and μ-PIGE, were used to investigate trace and essential element distributions in sections of normal and osteoarthritic (OA) human femoral head. μ-PIGE yielded 2-D mappings of Na and F while Ca, Z, P and S were mapped by μ-PIXE. The concentration of chondroitin sulphate supporting functionality in healthy cartilage is significantly reduced in OA samples. Localised Zn points to osteoblastic/osteoclastic activity at the bone-cartilage interface. Small-angle X-ray scattering applied to decalcified OA-affected tissue showed spatial alterations of collagen fibres of decreased axial periodicity compared to normal collagen type I.
Item Type: | Conference or Workshop Item (UNSPECIFIED) | ||||||||||||
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Divisions : | Surrey research (other units) | ||||||||||||
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Date : | 2012 | ||||||||||||
DOI : | 10.1063/1.3688820 | ||||||||||||
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Depositing User : | Symplectic Elements | ||||||||||||
Date Deposited : | 17 May 2017 12:23 | ||||||||||||
Last Modified : | 23 Jan 2020 17:48 | ||||||||||||
URI: | http://epubs.surrey.ac.uk/id/eprint/835140 |
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