University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Phase behaviour of a simple model of globular proteins

Sear, RP (1999) Phase behaviour of a simple model of globular proteins Journal of Chemical Physics v, 111. p4800-4806.

Full text not available from this repository.


A simple model of globular proteins which incorporates anisotropic attractions is proposed. It is closely related to models used to model simple hydrogen-bonding molecules such as water. Theories for both the fluid and solid phases are presented, and phase diagrams calculated. The model protein exhibits a fluid-fluid transition which is metastable with respect to the fluid-solid transition for most values of the model parameters. This is behaviour often observed for globular proteins. The model offers an explanation of the difficulty observed in crystallising some globular proteins and suggests that some proteins may not have a solid phase at all under all but extreme conditions.

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Date : 29 April 1999
DOI : 10.1063/1.479243
Uncontrolled Keywords : cond-mat.soft, cond-mat.soft, cond-mat.stat-mech, q-bio
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 11:28
Last Modified : 24 Jan 2020 20:53

Actions (login required)

View Item View Item


Downloads per month over past year

Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800