University of Surrey

Test tubes in the lab Research in the ATI Dance Research

In Vitro Activity of Epigallocatechin Gallate and Quercetin Alone and in Combination versus Clinical Isolates of Methicillin-Resistant Staphylococcus aureus

Betts, JW and Wareham, DW (2015) In Vitro Activity of Epigallocatechin Gallate and Quercetin Alone and in Combination versus Clinical Isolates of Methicillin-Resistant Staphylococcus aureus Journal of Natural Products, 78 (8). pp. 2145-2148.

Full text not available from this repository.

Abstract

Topical infections can become life threatening in immunocompromised patients. However, fewer treatments are available as multi-drug-resistant bacteria become more common. The natural compounds epigallocatechin gallate (1) and quercetin (2) alone and in combination were tested as potential antimicrobial clinical therapies. Strong antimicrobial activity was produced by 1 alone against methicillin-resistant Staphylococcus aureus, and activity was significantly increased in the presence of 2. A synergistic interaction was observed between the two compounds. Kill kinetics indicate the combination is bactericidal over 24 h.

Item Type: Article
Authors :
NameEmailORCID
Betts, JWjono.betts@surrey.ac.ukUNSPECIFIED
Wareham, DWUNSPECIFIEDUNSPECIFIED
Date : 12 August 2015
Identification Number : 10.1021/acs.jnatprod.5b00471
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:43
Last Modified : 17 May 2017 14:52
URI: http://epubs.surrey.ac.uk/id/eprint/828976

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800