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Interactions of typical and atypical enteropathogenic Escherichia coli strains with the calf intestinal mucosa ex vivo.

Girard, F, Dziva, F, Stevens, MP and Frankel, G (2009) Interactions of typical and atypical enteropathogenic Escherichia coli strains with the calf intestinal mucosa ex vivo. Appl Environ Microbiol, 75 (18). pp. 5991-5995.

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Abstract

Enteropathogenic Escherichia coli (EPEC) can be found in healthy and diarrheic cattle; however, little is known about the role of attaching and effacing (A/E) lesion formation in colonization of bovine intestinal mucosa by such strains. We show that typical and atypical EPEC induce A/E lesions on calf intestinal explants independently of Tir tyrosine phosphorylation and TccP. Our data support the existence of conserved Tir- and TccP-independent mechanisms of A/E lesion formation in a range of hosts and reinforce the zoonotic potential of EPEC in cattle.

Item Type: Article
Authors :
NameEmailORCID
Girard, FUNSPECIFIEDUNSPECIFIED
Dziva, Ff.dziva@surrey.ac.ukUNSPECIFIED
Stevens, MPUNSPECIFIEDUNSPECIFIED
Frankel, GUNSPECIFIEDUNSPECIFIED
Date : September 2009
Identification Number : https://doi.org/10.1128/AEM.01170-09
Uncontrolled Keywords : Animals, Bacterial Adhesion, Cattle, Enteropathogenic Escherichia coli, Escherichia coli Proteins, In Vitro Techniques, Intestinal Mucosa, Phosphorylation
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:39
Last Modified : 17 May 2017 10:39
URI: http://epubs.surrey.ac.uk/id/eprint/828667

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