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An inclusive dose pole for treatment of schistosomiasis in infants and preschool children with praziquantel.

Sousa-Figueiredo, JC, Day, M, Betson, M, Kabatereine, NB and Stothard, JR (2010) An inclusive dose pole for treatment of schistosomiasis in infants and preschool children with praziquantel. Trans R Soc Trop Med Hyg, 104 (11). pp. 740-742.

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Abstract

In large-scale interventions for control of schistosomiasis, use of the WHO dose pole is favoured for mass drug administration of praziquantel. Application of this simple tool has enabled pragmatic tablet dosing using patient height as a proxy for bodyweight, allowing control programmes to expand into resource-poor settings. Here we briefly summarize the inception and development of the existing WHO dose pole and discuss a proposed update which now permits dosing of infants and preschool children (height<94cm). Using this pole, we suggest that mass drug administration can be better optimized, streamlining general treatment to reduce drug wastage which could lead to significant programmatic savings and allocation of treatments to younger children with minimal additional cost.

Item Type: Article
Authors :
NameEmailORCID
Sousa-Figueiredo, JCUNSPECIFIEDUNSPECIFIED
Day, MUNSPECIFIEDUNSPECIFIED
Betson, Mm.betson@surrey.ac.ukUNSPECIFIED
Kabatereine, NBUNSPECIFIEDUNSPECIFIED
Stothard, JRUNSPECIFIEDUNSPECIFIED
Date : November 2010
Identification Number : 10.1016/j.trstmh.2010.07.012
Uncontrolled Keywords : Africa South of the Sahara, Anthelmintics, Body Height, Child, Preschool, Clinical Protocols, Cost-Benefit Analysis, Dose-Response Relationship, Drug, Female, Humans, Infant, Male, Praziquantel, Schistosomiasis, Treatment Outcome
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:33
Last Modified : 17 May 2017 14:50
URI: http://epubs.surrey.ac.uk/id/eprint/828286

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