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Psychiatric profiles of mothers who take Ecstasy/MDMA during pregnancy: reduced depression 1 year after giving birth and quitting Ecstasy.

Turner, JJ, Parrott, AC, Goodwin, J, Moore, DG, Fulton, S, Min, MO and Singer, LT (2014) Psychiatric profiles of mothers who take Ecstasy/MDMA during pregnancy: reduced depression 1 year after giving birth and quitting Ecstasy. J Psychopharmacol, 28 (1). pp. 55-61.

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BACKGROUND: The recreational drug MDMA (3,4-methylenedioxymethamphetamine) or 'Ecstasy' is associated with heightened psychiatric distress and feelings of depression. The Drugs and Infancy Study (DAISY) monitored the psychiatric symptom profiles of mothers who used Ecstasy/MDMA while pregnant, and followed them over the first year post-partum. METHODS: We compared 28 young women whom took MDMA during their pregnancy with a polydrug control group of 68 women who took other psychoactive drugs while pregnant. The Brief Symptom Inventory (BSI) was completed for several periods: The first trimester of pregnancy; and 1, 4 and 12 months after childbirth. Recreational drug use was monitored at each time point. RESULTS: During the first trimester of pregnancy, MDMA-using mothers reported higher depression scores than the polydrug controls. At 1 year after childbirth, their BSI depression scores were significantly lower, now closer to the control group values. At the same time point, their self-reported use of MDMA became nearly zero, in contrast to their continued use of Cannabis/marijuana, nicotine and alcohol. We found significant symptom reductions in those with BSI obsessive-compulsive and interpersonal sensitivity, following Ecstasy/MDMA cessation. CONCLUSIONS: The findings from this unique prospective study of young recreational drug-using mothers are consistent with previous reports of improved psychiatric health after quitting MDMA.

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Turner, JJ
Parrott, AC
Goodwin, J
Fulton, S
Min, MO
Singer, LT
Date : January 2014
DOI : 10.1177/0269881113515061
Uncontrolled Keywords : Cessation, Ecstasy, MDMA, depression, drug addiction, middle class, mother, post-partum, pregnancy, quitting, recreational drugs, Adult, Case-Control Studies, Depression, Drug Users, Female, Health Status, Humans, Mothers, N-Methyl-3,4-methylenedioxyamphetamine, Pregnancy, Psychiatric Status Rating Scales, Street Drugs, Stress, Psychological, Time Factors, Young Adult
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:30
Last Modified : 24 Jan 2020 19:28

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