University of Surrey

Test tubes in the lab Research in the ATI Dance Research

The Regulation of Human Sleep and Wakefulness: Sleep Homeostasis and Circadian Rhythmicity

Dijk, DJ and Lazar, AS (2012) The Regulation of Human Sleep and Wakefulness: Sleep Homeostasis and Circadian Rhythmicity

Full text not available from this repository.

Abstract

© 2012 by Oxford University Press, Inc. All rights reserved.The alternation of sleep and wakefulness is a major determinant of the structure and quality of our lives. The sleep- wake cycle is regulated by a fine-tuned balance between two physiological processes: sleep homeostasis, which measures sleep debt, and circadian rhythmicity, which determines the optimal internal (biological) time for sleep and wakefulness. Sleep homeostasis and circadian rhythmicity together influence many aspects of sleep, such as the time it takes to fall asleep, the timing of awakening and the interruptions of sleep, as well as the duration of rapid eye movement sleep, slow-wave sleep and specific brainwaves during sleep, such as sleep spindles. Alterations in the balance between sleep homeostasis and circadian rhythmicity contribute to sleep phenotypes such as morningness-eveningness and short-long sleepers as well as sleep disturbances. Emerging insights into the environmental, behavioral, physiological, neurochemical and molecular-genetic determinants of sleep homeostasis and circadian rhythmicity provide new avenues for the understanding and improvement of the sleep- wake cycle.

Item Type: Article
Authors :
NameEmailORCID
Dijk, DJd.j.dijk@surrey.ac.ukUNSPECIFIED
Lazar, ASUNSPECIFIEDUNSPECIFIED
Date : 18 September 2012
Identification Number : https://doi.org/10.1093/oxfordhb/9780195376203.013.0003
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:29
Last Modified : 17 May 2017 14:49
URI: http://epubs.surrey.ac.uk/id/eprint/828018

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800