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Pancreatic mixed acinar-endocrine carcinoma in a dog.

Belshaw, Z, Bacon, NJ, Foale, RD, Mannion, PM and Reuter, R (2005) Pancreatic mixed acinar-endocrine carcinoma in a dog. Vet Comp Oncol, 3 (3). pp. 145-148.

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A 10.5-year-old crossbreed dog was presented with a history of hypoglycaemic episodes and elevated serum insulin concentration. A pancreatic mass was removed at surgery along with an enlarged draining lymph node. An unresectable hepatic nodule was also present. Immunohistochemistry confirmed the pancreatic and lymph node masses as functional mixed acinar-endocrine carcinoma, previously unreported in domestic species. Persistent hypoglycaemia and hyperinsulinaemia post-operatively was highly suggestive of the hepatic mass being a functional metastasis. The dog was managed on prednisolone and remained asymptomatic 9 months post-operatively. This tumour type has only been rarely reported in human patients and may highlight the need for more rigorous immunohistochemical staining of pancreatic masses in veterinary species to identify the prevalence of this tumour type.

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Belshaw, Z
Foale, RD
Mannion, PM
Reuter, R
Date : September 2005
DOI : 10.1111/j.1476-5810.2005.00073.x
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:20
Last Modified : 24 Jan 2020 19:00

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