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Intraoperative radiation for limb sparing of the distal aspect of the radius without transcarpal plating in five dogs.

Boston, SE, Duerr, F, Bacon, N, Larue, S, Ehrhart, EJ and Withrow, S (2007) Intraoperative radiation for limb sparing of the distal aspect of the radius without transcarpal plating in five dogs. Vet Surg, 36 (4). pp. 314-323.

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Abstract

OBJECTIVES: To evaluate intraoperative irradiation (IORT) as a method of limb spare with preservation of the radiocarpal joint. STUDY DESIGN: Prospective case series. ANIMALS: Dogs (n=5) with stage II sarcoma of the distal aspect of the radius. METHODS: A bone segment containing the tumor was isolated surgically, treated by IORT, reimplanted, and secured by internal fixation. In 1 dog, the postradiation tumor bed was curetted and filled with bone cement. Dogs were administered alternating adriamycin and carboplatin starting 2 weeks after IORT and monitored at regular intervals. RESULTS: Four dogs had osteosarcoma and 1 had undifferentiated sarcoma. Implant failure (n=3), deep tissue infection (3), and pathologic fracture (3) resulted in amputation (3) or pancarpal plating (2). The dog with undifferentiated sarcoma was euthanatized because of suspected tumor recurrence 4 months postoperatively. Osteotomy healing was documented by radiography (1), histopathology (2), or by direct observation (2). CONCLUSIONS: A technique for limb-sparing surgery of the distal portion of the radius in dogs using IORT had advantages include healing of the autograft and a source for a perfectly fitting autograft but did not appear to offer any advantage with respect to infection rate. Long-term preservation of the radiocarpal joint was not successful. CLINICAL RELEVANCE: It was not possible to preserve the function of the radiocarpal joint and so this technique cannot be recommended currently. Further study is needed to evaluate whether or not IORT can be considered in combination with pancarpal plating and possibly curettage and cementation of the tumor to prevent subchondral bone collapse.

Item Type: Article
Authors :
NameEmailORCID
Boston, SEUNSPECIFIEDUNSPECIFIED
Duerr, FUNSPECIFIEDUNSPECIFIED
Bacon, Nn.bacon@surrey.ac.ukUNSPECIFIED
Larue, SUNSPECIFIEDUNSPECIFIED
Ehrhart, EJUNSPECIFIEDUNSPECIFIED
Withrow, SUNSPECIFIEDUNSPECIFIED
Date : June 2007
Identification Number : https://doi.org/10.1111/j.1532-950X.2007.00272.x
Uncontrolled Keywords : Animals, Bone Cements, Bone Neoplasms, Carboplatin, Combined Modality Therapy, Dog Diseases, Dogs, Doxorubicin, Female, Fracture Fixation, Internal, Intraoperative Care, Limb Salvage, Male, Postoperative Complications, Prospective Studies, Radiation, Ionizing, Sarcoma, Treatment Outcome
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:20
Last Modified : 17 May 2017 14:48
URI: http://epubs.surrey.ac.uk/id/eprint/827325

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