University of Surrey

Test tubes in the lab Research in the ATI Dance Research

The developing and restructuring superior cervical ganglion of guinea pigs (Cavia porcellus var. albina).

Toscano, CP, de Melo, MP, Matera, JM, Loesch, A and Ribeiro, AA (2009) The developing and restructuring superior cervical ganglion of guinea pigs (Cavia porcellus var. albina). Int J Dev Neurosci, 27 (4). pp. 329-336.

Full text not available from this repository.

Abstract

Post-natal development comprises both maturation (from newborn to adult) and ageing (from adult to senility) and, during this phase, several adaptive mechanisms occur in sympathetic ganglia, albeit they are not fully understood. Therefore, the present study aimed at detecting whether post-natal development would exert any effect on the size and number of a guinea pig's superior cervical ganglion (SCG) neurons. Twenty right SCGs from male subjects were used at four ages, i.e. newborn (7 days), young (30 days), adult (7 months) and old animals (50 months). Using design-based stereological methods the volume of ganglion and the total number of mononucleate and binucleate neurons were estimated. Furthermore, the mean perikaryal volume of mononucleate and binucleate neurons was estimated using the vertical nucleator. The main findings of this study were a combination of post-natal-dependent increases and decreases in some variables: (i) 27% increase in ganglion volume, (ii) 24% and 43% decreases in the total number of mono and binucleate neurons, respectively, and (iii) 27.5% and 40% decreases in the mean perikaryal volume of mono and binucleate neurons, respectively. Despite the fall in neuron numbers found here, post-natal development is not only associated with neuron loss, but also embraces other structural adaptive mechanisms, which are discussed in this paper.

Item Type: Article
Authors :
NameEmailORCID
Toscano, CPUNSPECIFIEDUNSPECIFIED
de Melo, MPUNSPECIFIEDUNSPECIFIED
Matera, JMUNSPECIFIEDUNSPECIFIED
Loesch, AUNSPECIFIEDUNSPECIFIED
Ribeiro, AAUNSPECIFIEDUNSPECIFIED
Date : June 2009
Identification Number : 10.1016/j.ijdevneu.2009.03.006
Uncontrolled Keywords : Animals, Animals, Newborn, Cell Shape, Guinea Pigs, Male, Neurons, Superior Cervical Ganglion
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:14
Last Modified : 17 May 2017 10:14
URI: http://epubs.surrey.ac.uk/id/eprint/826971

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800