University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Modeling transport processes and their implications for chemical disposition and action

Plant, N (2011) Modeling transport processes and their implications for chemical disposition and action pp. 59-82.

Full text not available from this repository.

Abstract

In silico modeling has been used for a considerable period of time to aid in the understanding of drug action in the body. Such applications are vital to help understand the body's response chemical exposure and hence predict drug action/ safety in vivo, as well as the extrapolation of such data from model animals to humans. However, until recently these models have not really included the role of active transport proteins in controlling drug disposition, which may influence the absorption, distribution and excretion of chemicals. This chapter will examine the development of in silico models for the increased understanding of drug transport processes, and how these can be used to aid in the prediction of an individual response to drug treatment. © 2011 Springer Science+Business Media, LLC.

Item Type: Article
Authors :
NameEmailORCID
Plant, Nn.plant@surrey.ac.ukUNSPECIFIED
Date : 1 December 2011
Identification Number : 10.1007/978-1-4419-7964-3_4
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:13
Last Modified : 17 May 2017 10:13
URI: http://epubs.surrey.ac.uk/id/eprint/826922

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800