Cellular localization of aquaporins along the secretory pathway of the lactating bovine mammary gland: an immunohistochemical study.
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Mobasheri, A, Kendall, BH, Maxwell, JE, Sawran, AV, German, AJ, Marples, D, Luck, MR and Royal, MD (2011) Cellular localization of aquaporins along the secretory pathway of the lactating bovine mammary gland: an immunohistochemical study. Acta Histochem, 113 (2). pp. 137-149.
Full text not available from this repository.Abstract
In this study we examined the cellular localization of aquaporins (AQPs) along the secretory pathway of actively lactating bovine mammary glands using immunohistochemistry. Mammary tissues examined included secretory ducts and acini, gland cisterns, teats, stromal and adipose tissues. Aquaporin 1 (AQP1) was localized in capillary endothelia throughout the mammary gland in addition to myoepithelial cells underlying teat duct epithelia. AQP2 and AQP6 were not detected and AQP9 was found only in leukocytes. AQP3 and AQP4 were observed in selected epithelial cells in the teat, cistern and secretory tubuloalveoli. AQP5 immunopositivity was prominent in the cistern. AQP3 and AQP7 were found in smooth muscle bundles in the teat, secretory epithelial cells and duct epithelial cells. These immunohistochemical findings support a functional role for aquaporins in the transport of water and small solutes across endothelial and epithelial barriers in the mammary gland and in the production and secretion of milk.
| Item Type: | Article | |||||||||||||||||||||||||||
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| Divisions : | Surrey research (other units) | |||||||||||||||||||||||||||
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| Date : | February 2011 | |||||||||||||||||||||||||||
| DOI : | 10.1016/j.acthis.2009.09.005 | |||||||||||||||||||||||||||
| Uncontrolled Keywords : | Animals, Aquaporins, Cattle, Female, Immunohistochemistry, Lactation, Mammary Glands, Animal | |||||||||||||||||||||||||||
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| Depositing User : | Symplectic Elements | |||||||||||||||||||||||||||
| Date Deposited : | 17 May 2017 10:11 | |||||||||||||||||||||||||||
| Last Modified : | 24 Jan 2020 18:41 | |||||||||||||||||||||||||||
| URI: | http://epubs.surrey.ac.uk/id/eprint/826792 |
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