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Reducing suffering in animal models and procedures involving seizures, convulsions and epilepsy.

Wolfensohn, S, Hawkins, P, Lilley, E, Anthony, D, Chambers, C, Lane, S, Lawton, M, Robinson, S, Voipio, HM and Woodhall, G (2013) Reducing suffering in animal models and procedures involving seizures, convulsions and epilepsy. J Pharmacol Toxicol Methods, 67 (1). pp. 9-15.

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Abstract

This report is based on discussions and submissions from an expert working group consisting of veterinarians, animal care staff and scientists with expert knowledge relevant to the field and aims to facilitate the implementation of the Three Rs (replacement, reduction and refinement) in the use of animal models or procedures involving seizures, convulsions and epilepsy. Each of these conditions will be considered, the specific welfare issues discussed, and practical measures to reduce animal use and suffering suggested. The emphasis is on refinement since this has the greatest potential for immediate implementation, and some general issues for refinement are summarised to help achieve this, with more detail provided on a range of specific refinements.

Item Type: Article
Authors :
NameEmailORCID
Wolfensohn, Ss.wolfensohn@surrey.ac.ukUNSPECIFIED
Hawkins, PUNSPECIFIEDUNSPECIFIED
Lilley, EUNSPECIFIEDUNSPECIFIED
Anthony, DUNSPECIFIEDUNSPECIFIED
Chambers, CUNSPECIFIEDUNSPECIFIED
Lane, SUNSPECIFIEDUNSPECIFIED
Lawton, MUNSPECIFIEDUNSPECIFIED
Robinson, SUNSPECIFIEDUNSPECIFIED
Voipio, HMUNSPECIFIEDUNSPECIFIED
Woodhall, GUNSPECIFIEDUNSPECIFIED
Date : January 2013
Identification Number : https://doi.org/10.1016/j.vascn.2012.09.001
Uncontrolled Keywords : Animal Husbandry, Animals, Disease Models, Animal, Epilepsy, Humans, Pain, Seizures
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:10
Last Modified : 17 May 2017 14:47
URI: http://epubs.surrey.ac.uk/id/eprint/826720

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