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EN2: a novel prostate cancer biomarker.

McGrath, SE, Michael, A, Morgan, R and Pandha, H (2013) EN2: a novel prostate cancer biomarker. Biomark Med, 7 (6). pp. 893-901.

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Abstract

Extensive efforts to identify a clinically useful biomarker for the diagnosis of prostate cancer have resulted in important insights into the biology of the disease, but no new test has been approved by regulatory authorities. The unmet need has also shifted to identifying biomarkers that not only diagnose prostate cancer but also indicate whether the patient has 'significant' disease. EN2 is a homeobox-containing transcription factor secreted specifically by prostate cancers into urine, where it can be detected by a simple ELISA assay. A number of studies have demonstrated the enormous potential of EN2 to address this unmet need and provide the urologist with a simple, cheap and efficient prostate cancer biomarker.

Item Type: Article
Authors :
NameEmailORCID
McGrath, SEUNSPECIFIEDUNSPECIFIED
Michael, Aa.michael@surrey.ac.ukUNSPECIFIED
Morgan, Rr.morgan@surrey.ac.ukUNSPECIFIED
Pandha, Hh.pandha@surrey.ac.ukUNSPECIFIED
Date : December 2013
Identification Number : https://doi.org/10.2217/bmm.13.115
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:03
Last Modified : 17 May 2017 14:46
URI: http://epubs.surrey.ac.uk/id/eprint/826184

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