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Molecular Analysis in Factor XI Deficiency.

Johnson, KM and McVey, JH (1999) Molecular Analysis in Factor XI Deficiency. In: UNSPECIFIED UNSPECIFIED, pp. 211-221.

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Abstract

Factor XI (FXI) is the zymogen precursor of an active serine protease that participates in the contact phase of coagulation. Synthesized in the liver, it circulates in the plasma in a noncovalent complex with high molecular weight kininogen (1) at a normal concentration of 5 μg/mL. (For clinical purposes, the normal range is defined as 50-150 U/dL) (2). FXI circulates as a homodimeric glycoprotein with a mass of 160 kDa.

Item Type: Book Section
Authors :
NameEmailORCID
Johnson, KMUNSPECIFIEDUNSPECIFIED
McVey, JHj.mcvey@surrey.ac.ukUNSPECIFIED
Date : 1999
Identification Number : https://doi.org/10.1385/1-59259-248-1:211
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:58
Last Modified : 17 May 2017 14:46
URI: http://epubs.surrey.ac.uk/id/eprint/825832

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