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Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele.

Kennedy, LJ, Quarmby, S, Happ, GM, Barnes, A, Ramsey, IK, Dixon, RM, Catchpole, B, Rusbridge, C, Graham, PA, Hillbertz, NS , Roethel, C, Dodds, WJ, Carmichael, NG and Ollier, WE (2006) Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele. Tissue Antigens, 68 (1). pp. 82-86.

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Abstract

Dogs exhibit a range of immune-mediated conditions including a lymphocytic thyroiditis which has many similarities to Hashimoto's thyroiditis in man. We have recently reported an association in Doberman Pinschers between canine hypothyroidism and a rare DLA class II haplotype that contains the DLA-DQA1*00101 allele. We now report a further series of 173 hypothyroid dogs in a range of breeds where a significant association with DLA-DQA1*00101 is shown.

Item Type: Article
Authors :
NameEmailORCID
Kennedy, LJUNSPECIFIEDUNSPECIFIED
Quarmby, SUNSPECIFIEDUNSPECIFIED
Happ, GMUNSPECIFIEDUNSPECIFIED
Barnes, AUNSPECIFIEDUNSPECIFIED
Ramsey, IKUNSPECIFIEDUNSPECIFIED
Dixon, RMUNSPECIFIEDUNSPECIFIED
Catchpole, BUNSPECIFIEDUNSPECIFIED
Rusbridge, Cc.rusbridge@surrey.ac.ukUNSPECIFIED
Graham, PAUNSPECIFIEDUNSPECIFIED
Hillbertz, NSUNSPECIFIEDUNSPECIFIED
Roethel, CUNSPECIFIEDUNSPECIFIED
Dodds, WJUNSPECIFIEDUNSPECIFIED
Carmichael, NGUNSPECIFIEDUNSPECIFIED
Ollier, WEUNSPECIFIEDUNSPECIFIED
Date : July 2006
Identification Number : 10.1111/j.1399-0039.2006.00614.x
Uncontrolled Keywords : Alleles, Animals, Dog Diseases, Dogs, Genes, MHC Class II, Histocompatibility Antigens Class II, Hypothyroidism
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:54
Last Modified : 17 May 2017 14:45
URI: http://epubs.surrey.ac.uk/id/eprint/825575

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