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Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele.

Kennedy, LJ, Quarmby, S, Happ, GM, Barnes, A, Ramsey, IK, Dixon, RM, Catchpole, B, Rusbridge, C, Graham, PA, Hillbertz, NS, Roethel, C, Dodds, WJ, Carmichael, NG and Ollier, WE (2006) Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele. Tissue Antigens, 68 (1). pp. 82-86.

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Abstract

Dogs exhibit a range of immune-mediated conditions including a lymphocytic thyroiditis which has many similarities to Hashimoto's thyroiditis in man. We have recently reported an association in Doberman Pinschers between canine hypothyroidism and a rare DLA class II haplotype that contains the DLA-DQA1*00101 allele. We now report a further series of 173 hypothyroid dogs in a range of breeds where a significant association with DLA-DQA1*00101 is shown.

Item Type: Article
Authors :
NameEmailORCID
Kennedy, LJUNSPECIFIEDUNSPECIFIED
Quarmby, SUNSPECIFIEDUNSPECIFIED
Happ, GMUNSPECIFIEDUNSPECIFIED
Barnes, AUNSPECIFIEDUNSPECIFIED
Ramsey, IKUNSPECIFIEDUNSPECIFIED
Dixon, RMUNSPECIFIEDUNSPECIFIED
Catchpole, BUNSPECIFIEDUNSPECIFIED
Rusbridge, Cc.rusbridge@surrey.ac.ukUNSPECIFIED
Graham, PAUNSPECIFIEDUNSPECIFIED
Hillbertz, NSUNSPECIFIEDUNSPECIFIED
Roethel, CUNSPECIFIEDUNSPECIFIED
Dodds, WJUNSPECIFIEDUNSPECIFIED
Carmichael, NGUNSPECIFIEDUNSPECIFIED
Ollier, WEUNSPECIFIEDUNSPECIFIED
Date : July 2006
Identification Number : https://doi.org/10.1111/j.1399-0039.2006.00614.x
Uncontrolled Keywords : Alleles, Animals, Dog Diseases, Dogs, Genes, MHC Class II, Histocompatibility Antigens Class II, Hypothyroidism
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:54
Last Modified : 17 May 2017 14:45
URI: http://epubs.surrey.ac.uk/id/eprint/825575

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