Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma.
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Betts, GN, Eustace, A, Patiar, S, Valentine, HR, Irlam, J, Ramachandran, A, Merve, A, Homer, JJ, Möller-Levet, C, Buffa, FM, Hall, G, Miller, CJ, Harris, AL and West, CM (2013) Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma. Eur J Cancer, 49 (1). pp. 156-165.
Full text not available from this repository.Abstract
Tumour hypoxia is associated with a poor prognosis in head and neck squamous cell carcinoma (HNSCC), however there is no accepted method for assessing hypoxia clinically. We aimed to conduct a technical validation of a hypoxia gene expression signature using the TaqMan Low Density Array (TLDA) platform to investigate if this approach reliably identified hypoxic tumours.
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| Date : | January 2013 | |||||||||||||||||||||||||||||||||||||||||||||
| Identification Number : | https://doi.org/10.1016/j.ejca.2012.07.028 | |||||||||||||||||||||||||||||||||||||||||||||
| Uncontrolled Keywords : | Adult, Aged, Aged, 80 and over, Carcinoma, Squamous Cell, Cell Hypoxia, Female, Gene Expression Profiling, Head and Neck Neoplasms, Humans, Immunohistochemistry, Male, Middle Aged, Neoplasm Staging, Real-Time Polymerase Chain Reaction, Reproducibility of Results, Reverse Transcriptase Polymerase Chain Reaction, Sensitivity and Specificity, Transcriptome | |||||||||||||||||||||||||||||||||||||||||||||
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| Depositing User : | Symplectic Elements | |||||||||||||||||||||||||||||||||||||||||||||
| Date Deposited : | 17 May 2017 09:52 | |||||||||||||||||||||||||||||||||||||||||||||
| Last Modified : | 17 May 2017 09:52 | |||||||||||||||||||||||||||||||||||||||||||||
| URI: | http://epubs.surrey.ac.uk/id/eprint/825423 |
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